- Original Article
- Factors Related to the Outcome of Neonatal Seizures
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Sung Koo Kim, Ran Lee, In Kyu Lee, Ki Joong Kim, Young Seung Hwang
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Clin Exp Pediatr. 2000;43(2):267-273. Published online February 15, 2000
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Purpose : Seizures during the neonatal period may be an important indicator of serious neurologic abnormalities and can cause permanent neurologic sequelae. We attempted to find and analyze the factors related to the outcome of neonatal seizures.
Methods : Seventy-six newborns with seizure were reviewed. The outcomes were analyzed according to etiologic diseases, gestational ages, characteristics of seizure, and neuroimaging and... |
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- The Apoptosis and Expression of Bcl-2, Bcl-xS, Bax Proteins in Fetal Brain after Treating Pregnant Mice with Endotoxin
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Sung Min Cho, Seung Sook Kim, Young Seung Hwang
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Clin Exp Pediatr. 2000;43(1):97-104. Published online January 15, 2000
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Purpose : Apoptosis is active cell death which plays an important role in developing normal tissues.
Various conditions such as genetic defects, drugs, ischemia or infections are known to induce
apoptosis. We studied the effect of maternal infection on fetal brain development during pregnancy.
Methods : We treated 46 C3H pregnant mice with lipopolysaccharide(LPS) or phosphat-buffered
saline and observed the changes in apoptosis and... |
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- Case Report
- A Pediatric Case of MELAS Syndrome Associated with Insulin-dependent Diabetes Mellitus
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Kyung Ran Park, Hye Won Park, Tae Sung Ko, Hae Il Cheong, Sei Won Yang, Young Seung Hwang, In Won Kim, Je Geun Chi
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Clin Exp Pediatr. 1996;39(10):1461-1465. Published online October 15, 1996
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MELAS(mitochondrial myopathy, encephalopathy, lactic acidosis, and sroke like episodes) is a
major subgroup of heterogeneous mitochondrial encephalopathy. Recent advances in molecular
genetics revealed specific mutations in the mitochondrial DNA causing MELAS. We described
clinical and molecular genetic findings of a 13-year-old boy with MELAS syndrome associated
IDDM(insulin dependent diabetes mellitus). For molecular genetic studies, DNAs from peripheral
blood nucleated cells were used. And the A→G... |
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